5-Amino-1MQ 50 mg

How it works

5-Amino-1MQ is frequently marketed and searched for as a "peptide," but that label is chemically inaccurate. The compound, formally 5-amino-1-methylquinolinium, is a small synthetic molecule rather than a chain of amino acids, and it is listed as such in chemical databases like PubChem and the FDA's Global Substance Registration System.^[1] It is studied as a selective, membrane-permeable inhibitor of an enzyme called nicotinamide N-methyltransferase, or NNMT.

Because online body-composition and longevity content often lumps metabolic research compounds together with true peptides, 5-Amino-1MQ shows up in peptide-therapy searches despite its distinct chemical class. Common naming variants include 5-Amino-1MQ, 5-amino-1-methylquinolinium, 5-AMQ, and 5A-1MQ, all referring to the same research molecule.

Benefits & side effects

The evidence for 5-Amino-1MQ is preclinical. In diet-induced-obese mice, the compound reduced body weight, white-fat mass, adipocyte size, and cholesterol without reducing food intake.^[2] A follow-up mouse study combining an NNMT inhibitor with a reduced-calorie diet reported improvements in body composition and liver fat compared with diet change alone.^[5] Separate mouse work examined aged muscle and exercise responses, while a pharmacokinetic study characterized the compound in rats rather than people.^[6][13]

No registered or completed human efficacy study of 5-Amino-1MQ was identified in the sources reviewed through August 10, 2026.^[20] Claims about human fat loss, longevity, mitochondrial health, or disease treatment therefore remain extrapolations from animal and cell experiments.