Evidence & concentration worksheet · Experimental Research

Adipotide 10 mg

Human efficacy and a validated dose have not been established for this compound. The former regimen has been withheld; only concentration arithmetic remains available.

D

Evidence review

No established human dosing protocol

Human efficacy and a validated dose have not been established for this compound. The former regimen has been withheld; only concentration arithmetic remains available.

How it works

Adipotide, also called FTPP or prohibitin-targeting peptide 1, is an experimental peptidomimetic designed to target blood vessels that supply white adipose tissue and trigger programmed cell death. It is not an appetite hormone and has no FDA-approved product, indication, or dose.

Benefits & side effects

A 2011 study in obese rhesus monkeys reported reduced weight and white-fat volume and improved insulin-resistance measures during treatment.[1] The same study found dose-related kidney proximal-tubule changes, including degeneration and regeneration; measured kidney-function changes reversed after treatment stopped.[1]

A registered first-in-human phase 1 study enrolled people with metastatic prostate cancer and obesity to assess tolerability and dose limits, not to establish routine obesity treatment.[2] Teloryx found no published controlled human efficacy trial supporting adipotide for weight loss.

Calculator

Concentration and measurement calculator

Use this only to check arithmetic from an authoritative product label, registered study protocol, or qualified clinician.

Arithmetic only — not a dose recommendation

Enter only a concentration and target supplied by an authoritative product label, a registered study protocol, or a qualified clinician. A correct conversion does not establish that a substance, vial, route, or dose is safe or effective.

Arithmetic only — not a dose recommendation

Enter only a concentration and target supplied by an authoritative product label, a registered study protocol, or a qualified clinician. A correct conversion does not establish that a substance, vial, route, or dose is safe or effective.

1

Source concentration

mg
mL
Concentration
Per unit (0.01 mL)
Per 10 units (0.1 mL)
2

Source-supplied target

Calculated U-100 volume units =

References

References

  1. Science Translational MedicineA peptidomimetic targeting white fat in obese monkeys (2011)
  2. ClinicalTrials.govFirst-in-man phase I evaluation of prohibitin-targeting peptide 1 (2012)
  3. U.S. FDAInvestigational New Drug application (2025)