Evidence & concentration worksheet · Experimental Research
Adipotide 10 mg
Human efficacy and a validated dose have not been established for this compound. The former regimen has been withheld; only concentration arithmetic remains available.
Evidence review
No established human dosing protocol
Human efficacy and a validated dose have not been established for this compound. The former regimen has been withheld; only concentration arithmetic remains available.
How it works
Adipotide, also called FTPP or prohibitin-targeting peptide 1, is an experimental peptidomimetic designed to target blood vessels that supply white adipose tissue and trigger programmed cell death. It is not an appetite hormone and has no FDA-approved product, indication, or dose.
Benefits & side effects
A 2011 study in obese rhesus monkeys reported reduced weight and white-fat volume and improved insulin-resistance measures during treatment.[1] The same study found dose-related kidney proximal-tubule changes, including degeneration and regeneration; measured kidney-function changes reversed after treatment stopped.[1]
A registered first-in-human phase 1 study enrolled people with metastatic prostate cancer and obesity to assess tolerability and dose limits, not to establish routine obesity treatment.[2] Teloryx found no published controlled human efficacy trial supporting adipotide for weight loss.
Calculator
Concentration and measurement calculator
Use this only to check arithmetic from an authoritative product label, registered study protocol, or qualified clinician.
Arithmetic only — not a dose recommendation
Enter only a concentration and target supplied by an authoritative product label, a registered study protocol, or a qualified clinician. A correct conversion does not establish that a substance, vial, route, or dose is safe or effective.
Enter only a concentration and target supplied by an authoritative product label, a registered study protocol, or a qualified clinician. A correct conversion does not establish that a substance, vial, route, or dose is safe or effective.
Source concentration
Source-supplied target
References
References
- Science Translational Medicine — A peptidomimetic targeting white fat in obese monkeys (2011)
- ClinicalTrials.gov — First-in-man phase I evaluation of prohibitin-targeting peptide 1 (2012)
- U.S. FDA — Investigational New Drug application (2025)