Dosage protocol · Growth Hormone & Performance
PEG MGF 2 mg
Typical daily range: 200–500 mcg once daily (gradual titration over 8 weeks).
- Reconstitute: Add 3.0 mL bacteriostatic water (max vial capacity) → ~0.667 mg/mL concentration.
- Typical daily range: 200–500 mcg once daily (gradual titration over 8 weeks).
- Easy measuring: At 0.667 mg/mL, 1 unit = 0.01 mL ≈ 6.67 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
Reconstitution
PEG MGF dosage chart
| Week | Dose | Draw |
|---|---|---|
| Weeks 1–2 | 200 mcg | 30 units0.30 mL |
| Weeks 3–4 | 300 mcg | 45 units0.45 mL |
| Weeks 5–6 | 400 mcg | 60 units0.60 mL |
| Weeks 7–8 | 500 mcg | 75 units0.75 mL |
How much to draw
The Draw column shows exactly where to stop on a U-100 insulin syringe. Different vial size or dose? The calculator below recomputes it live.
Supplies needed
Supplies needed
Peptide vial
The lyophilized compound
Bacteriostatic water
For reconstitution
U-100 insulin syringes
One per injection
Alcohol swabs
Stopper + site each time
How it works
PEG-MGF is a synthetic peptide made by attaching polyethylene glycol (PEG) to a peptide related to mechano growth factor, or MGF. MGF is the informal name for a splice variant of insulin-like growth factor 1 (IGF-1), sometimes called the IGF-1 E-peptide, that the body produces locally in skeletal muscle in response to mechanical loading or damage.[3]
PEG-MGF is not an approved medicine. It is a lab-modified, exogenous version of that natural signaling peptide, marketed mainly in fitness and research-chemical circles for muscle repair and growth, with the PEGylation intended to slow clearance and extend how long the peptide remains active in circulation.[13]
Benefits & side effects
The evidence that actually exists is almost entirely about endogenous MGF, not the injected PEGylated version. Studies measuring MGF-related gene expression after exercise, plus animal and cell-culture experiments manipulating local IGF-1 isoforms, support the general idea that this signaling family matters for muscle adaptation and regeneration.[5] [6]
Direct clinical evidence for PEG-MGF as an injected therapy is essentially absent: public drug and clinical-trial databases show no approved product or registered human trial under this name.[1] [2] The wealth of online claims about lean-muscle gains and faster recovery comes from anecdotal bodybuilding reports rather than controlled studies, and those reports typically involve unverified product identity and dosing, often alongside concurrent use of other performance-enhancing substances, which makes them unreliable evidence of PEG-MGF's own effect.
Calculator
Plan your own dose
Reconstituting a different vial size or targeting a different dose? Run the numbers.