Evidence & concentration worksheet · Skin & Cosmetic
SNAP-8 10 mg
Human efficacy and a validated dose have not been established for this compound. The former regimen has been withheld; only concentration arithmetic remains available.
Evidence review
No established human dosing protocol
Human efficacy and a validated dose have not been established for this compound. The former regimen has been withheld; only concentration arithmetic remains available.
How it works
SNAP-8 is a trade name for acetyl octapeptide-3 used in topical cosmetics. It is not botulinum toxin, not an injectable treatment, and not an FDA-approved drug. Finished serums also contain vehicles, preservatives, and other actives that affect penetration, tolerability, and performance.
Benefits & side effects
The commonly cited peer-reviewed human study concerns acetyl hexapeptide-8 (Argireline), a related but different molecule—not acetyl octapeptide-3.[1] Manufacturer percentages, mechanism diagrams, and findings for a related peptide do not establish that every SNAP-8 formulation reduces wrinkles. Teloryx found no robust independent randomized human trial directly validating SNAP-8 itself.
Calculator
Concentration and measurement calculator
Use this only to check arithmetic from an authoritative product label, registered study protocol, or qualified clinician.
Arithmetic only — not a dose recommendation
Enter only a concentration and target supplied by an authoritative product label, a registered study protocol, or a qualified clinician. A correct conversion does not establish that a substance, vial, route, or dose is safe or effective.
Enter only a concentration and target supplied by an authoritative product label, a registered study protocol, or a qualified clinician. A correct conversion does not establish that a substance, vial, route, or dose is safe or effective.
Source concentration
Source-supplied target
References
References
- International Journal of Cosmetic Science — A synthetic hexapeptide with antiwrinkle activity (2002)
- U.S. FDA — FDA authority over cosmetics (2026)
- U.S. FDA — What to do if you have a reaction to cosmetics (2026)