Encyclopedia · Experimental Research

Adipotide Peptide Guide

Evidence review

Evidence grade D

Evidence is primarily from animal and laboratory studies; human efficacy and an established dose are absent.

Reviewed Aug 10, 2026 3 linked authoritative sources

Adipotide, also called FTPP or prohibitin-targeting peptide 1, is an experimental peptidomimetic designed to target blood vessels that supply white adipose tissue and trigger programmed cell death. It is not an appetite hormone and has no FDA-approved product, indication, or dose.

What adipotide is

Adipotide, also called FTPP or prohibitin-targeting peptide 1, is an experimental peptidomimetic designed to target blood vessels that supply white adipose tissue and trigger programmed cell death. It is not an appetite hormone and has no FDA-approved product, indication, or dose.

Weight-loss evidence comes from animals

A 2011 study in obese rhesus monkeys reported reduced weight and white-fat volume and improved insulin-resistance measures during treatment.[1] The same study found dose-related kidney proximal-tubule changes, including degeneration and regeneration; measured kidney-function changes reversed after treatment stopped.[1]

A registered first-in-human phase 1 study enrolled people with metastatic prostate cancer and obesity to assess tolerability and dose limits, not to establish routine obesity treatment.[2] Teloryx found no published controlled human efficacy trial supporting adipotide for weight loss.

Safety uncertainty is central, not incidental

The proposed mechanism deliberately injures selected vasculature, and kidney toxicity appeared in nonhuman primates. Human long-term kidney, cardiovascular, off-target vascular, cancer, pregnancy, and interaction risks are not established. An investigational-new-drug authorization permits research; it is not evidence of safety or effectiveness and is not marketing approval.[3]

Regulatory status

Adipotide is unapproved in the United States. Online “research-grade” material is not the clinical-trial product and has no FDA-reviewed identity, purity, sterility, labeling, or prescribing information. Teloryx does not publish an adipotide dose, cycle, stack, or reconstitution recipe.

Evidence review

Sources and evidence

Citation numbers in the article link to the exact regulator records, trial registrations, and publications reviewed.

  1. Science Translational MedicineA peptidomimetic targeting white fat in obese monkeys (2011)
  2. ClinicalTrials.govFirst-in-man phase I evaluation of prohibitin-targeting peptide 1 (2012)
  3. U.S. FDAInvestigational New Drug application (2025)